*Corresponding author
2016
Clinical Electroencephalogram Biomarker for Seizures in Asymptomatic Tuberous Sclerosis Complex Infants
Wu JY, Peters JM; Goyal M, Krueger D, Sahin M, Northrup H, Au KS, Cutter G, Bebin EM Pediatr Neurol. 2016 Jan;54:29-34
2016
Visual Evoked Potentials in Infants with Tuberous Sclerosis Complex
Varcin KJ, Nelson CA Sahin M, Wu JY, Jeste SS J Child Neurol. 2016 Feb;31(2):195-202
2016
Cell type-specific miR-431 dysregulation in a motor neuron model of Spinal Muscular Atrophy
Wertz MH, Winden K, Neveu P, Ng S-Y, 4, Ercan E, Sahin M Hum Mol Genet 2016
2015
A Vascular Model of Tsc1 Deficiency Accelerates Renal Tumor Formation with Accompanying Hemangiosarcomas
Leech JD, Lammers SH, Goldman S, Auricchio N, Bronson RT, Kwiatkowski DJ, Sahin M. Mol Cancer Res. 2015 Mar;13(3):548-55
2015
Disorders of Microtubule Function in Neurons: Imaging Correlates
Mutch CA, Poduri A, Sahin M, Barry B, Walsh CA, Barkovich AJ AJNR Am J Neuroradiol. 2015 Nov 12. [Epub ahead of print]
2015
Autism and the Synapse: Emerging Mechanisms and Mechanism-based Therapies
Ebrahimi-Fakhari D. and Sahin M. Curr Opin Neurol. 2015 Apr;28(2):91-102
2015
Super-resolution reconstruction in frequency, image, and wavelet domains to reduce through-plane partial voluming in MRI
Gholipour A, Afacan O, Aganj I, Scherrer B, Prabhu SP, Sahin M, Warfield SK Med Phys. 2015 42(12): 6919–6932
2015
The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation
Lipton JO, Yuan ED, Boyle LM, Ebrahimi-Fakhari D, Kwiatkowski E, Nathan A, Guttler T, Davis F, Asara JM, and Sahin M. Cell. 2015 May 21; 161(5):1138-51
2015
Longitudinal Changes in Diffusion Properties of White Matter Pathways of Children With Tuberous Sclerosis Complex
Baumer FM, Song JW, Mitchell PD, Pienaar R, Sahin M, Grant PE, Takahasi E. Pediatr Neurol. 2015 Jun;52(6):615-23
2015
Tuberous Sclerosis Complex
DiMario FJ Jr, Sahin M, Ebrahimi-Fakhari, D. Pediatr Clin North Am. 2015 Jun;62(3):633-648
2015
Genes, Circuits, and Precision Therapies for Autism and Related Neurodevelopmental Disorders
Sahin M and Sur M. Science 2015 Nov 20;350(6263). pii: aab3897
2015
Tubers are neither static nor discrete: Evidence from serial diffusion tensor imaging
Peters JM, Prohl AK, Tomas-Fernandez XK, Taquet M, Scherrer B, Prabhu SP, Lidov HG, Singh JM, Floor Elisabeth Jansen, Braun KPJ, Sahin M, Warfield SK, and Stamm A Neurology 2015 3;85(18):1536-45
2015
The Stress-Induced Atf3-gelsolin Cascade Underlies Dendritic Spine Deficits in Neuronal Models of Tuberous Sclerosis Complex
76. Nie D, Chen Z, Julich K, Robson VK, Di Nardo A, Cheng Y-C, Woolf CJ, Heiman M, Sahin M J. Neurosci 2015; 35(30):10762-10772
2015
Cerebellar associative sensory learning defects in five mouse autism models
77. Kloth AD, Badura A, Li A, Cherskov A, Connolly SG, Giovannucci A, Bangash MA, Grasselli G, Peñagarikano O, Piochon C, Tsai PT, Geschwind DH, Hansel C, Sahin M, Takumi T, Worley PF, and Wang SS-H eLife 2015;4:e06085
2015
Mosaic and intronic mutations in TSC1/TSC2 explain the majority of TSC patients with no mutation identified by conventional testing
Tyburczy ME, Dies KA, Glass J, Camposano S, Chekaluk Y, Thorner A, Van Hummelen P, Krueger D, DFranz D, Thiele EA, Sahin M, Kwiatkowski DJ PLoS Genet. 2015 Nov 5;11(11):e1005637
2015
Tuberous Sclerosis Associated Neuropsychiatric Disorders (TAND) and the TAND Checklist
de Vries PJ, Whittemore VH, Leclezio L, Byars AW, Dunn D, Ess KC, Hook D, King BH, Sahin M, Jansen A. Pediatr Neurol. 2015 Jan; 52(1): 25-35
2015
Characterizing brain tissue by assessment of the distribution of anisotropic microstructural environments in diffusion-compartment imaging (DIAMOND)
Scherrer B, Schwartzman A, Taquet M, Sahin M, Prabhu SP, Warfield SK Magn Reson Med. 2015 Sep 12. doi: 10.1002/mrm.25912. [Epub ahead of print]
2014
Neuronal Tsc1/2 complex controls autophagy through AMPK dependent regulation of ULK1.
Di Nardo A, Wertz MH, Kwiatkowski E, Tsai PT, Leech JD, Greene-Colozzi E, Goto J, Dilsiz P, Talos DM, Clish CB, Kwiatkowski DJ, Sahin M. Hum Mol Genet, 2014 Mar 18
2012
Autistic-like behavior and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice.
Tsai PT, Hull C, Chu YX, Greene-Colozzi E, Sadowski A, Leech JM, Steinberg J, Crawley JN, Regehr WG, Sahin M. * Nature, 2012 Jul 1. doi: 10.1038/nature11310
2012
Prenatal rapamycin results in early and late behavioral abnormalities in wildtype C57BL/6 mice.
Tsai, Peter T, Greene-Colozzi, Emily, Goto, June, Anderl, Stefanie, Kwiatkowski, David J, Sahin, Mustafa. Behavior genetics. 2012
2012
Graded Loss of Tuberin in an Allelic Series of Brain Models of TSC Correlates with Survival, and Biochemical, Histological, and Behavioral Features.
Yuan, Elizabeth, Tsai, Peter T, Greene-Colozzi, Emily, Sahin, Mustafa, Kwiatkowski, David J, Malinowska, Izabela A.  Human molecular genetics. 2012
2012
A genetic model to dissect the role of Tsc-mTORC1 in neuronal cultures.
Nie, Duyu, Sahin, Mustafa Methods in molecular biology (Clifton, N.J.). 2012
2011
Translational research: Rett syndrome and tuberous sclerosis complex.
Khwaja, Omar S, Sahin, Mustafa Current opinion in pediatrics.
2011
Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex.
Goto, June, Talos, Delia M, Klein, Peter, Qin, Wei, Chekaluk, Yvonne I, Anderl, Stefanie, Malinowska, Izabela A, Di Nardo, Alessia, Bronson, Roderick T, Chan, Jennifer A, Vinters, Harry V, Kernie, Steven G, Jensen, Frances E, Sahin, Mustafa, Kwiatkowski, David J.  Proceedings of the National Academy of Sciences of the United States of America. 
2011
TSC1/TSC2 Signaling in the CNS.
Han JM, Sahin M FEBS Lett.
2011
Mechanisms of neurocognitive dysfunction and therapeutic considerations in tuberous sclerosis complex.
Tsai P, Sahin M Curr Opin Neurol.
2011
Interaction of SMN and HuD with cpg15 mRNA rescues motor neuron axonal deficits.
Akten B, Kye MJ, Hao LT, Wertz MH, Singh S, Nie D, Huang J, Merianda TT, Twiss JL, Beattie CE, Steen J, Sahin M. Proc Natl Acad Sci U S A. 2011;108(25):10337-42.
2011
SMN Deficiency Reduces Cellular Ability to Form Stress Granules, Sensitizing Cells to Stress
Zou T, Yang X, Pan D, Huang J, Sahin M, Zhou J.  Cell Mol Neurobiol
2011
Impaired Language Pathways in Tuberous Sclerosis Complex Patients with Autism Spectrum Disorders.
Lewis, William W, Sahin, Mustafa, Scherrer, Benoit, Peters, Jurriaan M, Suarez, Ralph O, Vogel-Farley, Vanessa K, Jeste, Shafali S, Gregas, Matthew C, Prabhu, Sanjay P, Nelson, Charles A, Warfield, Simon K. Cereb Cortex. 2011
2011
Targeted treatment trials for tuberous sclerosis and autism: no longer a dream.
Sahin, Mustafa Curr Opin Neurobiol
2011
Loss of white matter microstructural integrity is associated with adverse neurological outcome in tuberous sclerosis complex.
Peters, Jurriaan M, Sahin, Mustafa, Vogel-Farley, Vanessa K, Jeste, Shafali S, Nelson, Charles A, Gregas, Matthew C, Prabhu, Sanjay P, Scherrer, Benoit, Warfield, Simon K. Acad Radiol
2010
TSC2-Rheb signaling regulates EphA-mediated axon guidance.
Nie D, Di Nardo A, Han JM, Baharanyi H, Kramvis I, Huynh T, Dabora S, Codeluppi S, Pandolfi PP, Pasquale EB, Sahin M. Nat Neurosci 2010;13:163–172. PMC2812631.
2010
Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits
Akten, Bikem, Kye, Min Jeong, Hao, Le T, Wertz, Mary H, Singh, Sasha, Nie, Duyu, Huang, Jia, Merianda, Tanuja T, Twiss, Jeffery L, Beattie, Christine E, Steen, Judith A J, Sahin, Mustafa Proc Natl Acad Sci U S A. 
2010
Diffusion Features of White Matter in Tuberous Sclerosis With Tractography.
Krishnan ML, Commowick O, Jeste SS, Weisenfeld N, Hans A, Gregas MC, Sahin M, Warfield SK. Pediatr Neurol
2010
Tsc2-Rheb signaling regulates EphA-mediated axon guidance.
Nie D, Di Nardo A, Han JM, Baharanyi H, Kramvis I, Huynh T, Dabora S, Codeluppi S, Pandolfi PP, Pasquale EB, Sahin M Nat Neurosci.
2009
The syndrome of perisylvian polymicrogyria with congenital arthrogryposis.
Poduri A, Chitsazzadeh V, D'Arrigo S, Fedrizzi E, Pantaleoni C, Riva D, Busse C, Küster H, Duplessis A, Gaitanis J, Sahin M, Garganta C, Topcu M, Dies KA, Barry BJ, Partlow J, Barkovich AJ, Walsh CA, Chang BS.  Brain Dev
2009
Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner.
Di Nardo A, Kramvis I, Cho N, Sadowski A, Meikle L, Kwiatkowski DJ, Sahin M J Neurosci
2008
Tuberous sclerosis complex proteins control axon formation.
Choi YJ, Di Nardo A, Kramvis I, Meikle L, Kwiatkowski DJ, Sahin M, He X.  Genes Dev 2008;22:2485-95
2008
Human CHN1 mutations hyperactivate alpha2-chimaerin and cause Duane's retraction syndrome
Miyake N, Chilton J, Psatha M, Cheng L, Andrews C, Chan WM, Law K, Crosier M, Lindsay S, Cheung M, Allen J, Gutowski NJ, Ellard S, Young E, Iannaccone A, Appukuttan B, Stout JT, Christiansen S, Ciccarelli ML, Baldi A, Campioni M, Zenteno JC, Davenport D, Mariani LE, Sahin M, Guthrie S, Engle EC.  Science
2008
Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function
Meikle L, Pollizzi K, Egnor A, Kramvis I, Lane H, Sahin M, Kwiatkowski DJ.  J Neurosci
2008
Tuberous sclerosis complex proteins control axon formation.
Choi YJ, Di Nardo A, Kramvis I, Meikle L, Kwiatkowski DJ, Sahin M, He X.  Genes Dev 2008;22:2485-95
2008
Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis
Ozcan U, Ozcan L, Yilmaz E, Düvel K, Sahin M, Manning BD, Hotamisligil GS.  Mol Cell
2008
Clinical presentation and diagnosis of tuberous sclerosis complex in infancy
Datta AN, Hahn CD, Sahin M. J Child Neurol
2007
Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway
Park KK, Liu K, Hu Y, Smith PD, Wang C, Cai B, Xu B, Connolly L, Kramvis I, Sahin M, He Z. Science
2007
Characterization of autism in young children with tuberous sclerosis complex
Jeste SS, Sahin M, Bolton P, Ploubidis GB, Humphrey A J Child Neurol
2007
Neonatal subependymal giant cell astrocytoma: new case and review of literature
Raju GP, Urion DK, Sahin M Pediatr Neurol
2006
S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt
Zhang HH, Lipovsky AI, Dibble CC, Sahin M, Manning BD Mol Cell
2005
Eph-dependent tyrosine phosphorylation of ephexin1 modulates growth cone collapse
Sahin M, Greer PL, Lin MZ, Poucher H, Eberhart J, Schmidt S, Wright TM, Shamah SM, O'connell S, Cowan CW, Hu L, Goldberg JL, Debant A, Corfas G, Krull CE, Greenberg ME Neuron
Tuberous Sclerosis: A New Frontier in Targeted Treatment of Autism.