Kellen Winden, MD, PhD
Education
BS, University of California San Diego, 2004
San Diego, CA
MD, University of California, Los Angeles, 2012
Los Angeles, CA
PhD, University of California, Los Angeles, 2011
Los Angeles, CA
Related Publications
- Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin
- Abnormal mTOR Activation in Autism
- Biallelic mutations in TSC2 lead to abnormalities associated with cortical tubers in human iPSC-derived neurons
- 16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro
- Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia
- Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts
- Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profile
- Translating Ribosome Affinity Purification (TRAP) of Cell Type-specific mRNA from Mouse Brain Lysates.