Recent Articles about the Sahin Laboratory

16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is recused by RHOA inhibition in vitro

(Nature Communications)

New technique yields potential treatment for a common cause of autism

(BCH Science)

Recommendations in reproducibility in stem cell research

(BCH Science)

Studies of tuberous sclerosis may shed light on biology of autism


Earlier treatment may help reverse autism-like behavior in tuberous sclerosis


Lab-grown Human Cerebellar Cells Yield Clues to Autism

Early Seizures Linked to Severe Form of Tuberous Sclerosis

Identifying the Roots of Myelin Dysfunction in the TSC Brain

Researchers identify new cause of brain defects in tuberous sclerosis patients
(Medical Express)

Impaired recycling of mitochondria in autism?
(Medical Express)

Circadian rhythms, protein production and disease
(Vector - Boston Children's Hospital)

Timing is Everything
(Harvard School of Medicine News)

Human Neuron Core to Scale Up Neuroscience
(Vector - Boston Children's Hospital) 

Cure SMA Awards Grant to Mustafa Sahin
(Cure SMA) 

Autism's Unexpected Link to Cancer Gene
(New York Times)

Brain Network Analysis Furthers Understanding of Autsim
(Autism Speaks - Science)

Could “network” analysis of the brain explain autism’s features?
(Vector - Boston Children's Hospital) 

Notable Papers of 2012
(Simons Foundation Autism Research Initiative News)

Trials for Neurodevelopmental Disorders
(Translational Research Program Newsletter)

Cognition and behavior: Connectivity link autism, TSC
(Simons Foundation Autism Research Initiative News)

Tuberous Sclerosis gene loss triggers autism-like features 
(Simons Foundation Autism Research Initiative News)

Insights for Autism from Tuberous Sclerosis Complex
(Simons Foundation Autism Research Initiative News)

Spinal Muscular Atrophy: Helping nerve fibers find their way
(Boston Children's Hospital Vector)

One Gene, One Drug Affect Autism Behaviors in Mouse Model 
(Autism Speaks)

Brain connectivity and TSC
(Boston Children's Hospital)

Tuberous sclerosis linked to brain cell migration
(Simons Foundation Autism Research Initiative News)

Can drugs improve cognitive deficits in developmental disorders? 
(Boston Children's Hospital News Room)

Children's Hospital Top Ten for 2010 in Science and Innovation
(Boston Children's Hospital News Room)

MIT soccer star Karenna Groff a huge success on and off the field

(CBS News Boston)​

Research Articles from the Sahin Laboratory

Big Cells in “Little Brain” may be Involved with Autism
(National Institute of Neurological Disorders and Stroke)

Autistic-like behavior and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice
(National Insitute for Health)

Charting Autism's Neural Circuits
(Harvard Medical School)